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  • Author(s):
    Zhongmou Chao, Kutay Sezginel, Ke Xu, Garrison Crouch, Abigale Gray, Christopher Wilmer, Paul Bohn, David Go, Susan Fillerton-Shirey
    Abstract:

    Silver nanofilament formation dynamics are reported for an ionic liquid (IL)-filled solid polymer electrolyte prepared by a direct-write process using a conductive atomic force microscope (C-AFM). Filaments are electrochemically formed at hundreds of xy locations on a ≈40 nm thick polymer electrolyte, polyethylene glycol diacrylate (PEGDA)/[BMIM]PF6. Although the formation time generally decreases with increasing bias from 0.7 to 3.0 V, an unexpected non-monotonic maximum is observed ≈2.0 V. …

    Date Published:
    2019-01
    Record Visibility:
    Public
  • Author(s):
    Jason Mason, Jordan A. Cockfield, Daniel Pape, Hannah Meissner, Michael Sokolowski, Taylor C. White, Jose Valentin Lopez, Juan Liu, Xiaojing Liu, Inmaculada martinez-Reyes, Navdeep Chandel, Jason Locasale, Zachary Schafer
    Abstract:

    Loss of integrin-mediated attachment to extracellular matrix (ECM) proteins can trigger a variety of cellular changes that impact cell viability. Foremost among these is the activation of anoikis, caspase-mediated cell death induced by ECM-detachment. In addition to anoikis, loss of ECM-attachment causes profound alterations in cellular metabolism that can lead to anoikis-independent cell death. Here, we describe a surprising role for serum and glucocorticoid kinase-1 (SGK1) in the promotion …

    Date Published:
    2020-03
    Record Visibility:
    Public
  • Author:
    Craig Reingold
    Advisory Committee:
    Anna M. Simon
    Degree Area:
    Physics
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-06-26
    Record Visibility:
    Public
  • Author(s):
    Sasha Padilla-Coley, Hui Xu
    Abstract:

    hydrophobic (i.e., Hoechst 33342) dyes or drugs, including a binary dye/drug pair (i.e., indocyanine green/mitoxantrone). The core of HBPn, containing a mixture of uncharged 2-pentanone chains and 1,2,3-triazole rings, could be loaded with uncharged and very hydrophobic dyes (i.e., Nile Red) or drugs. Improved aqueous solubility of camptothecin was achieved 10-fold from 8.4 to 75 ng/mL. Additionally, cell toxicity studies showed that HBPn was able to release the camptothecin drug inside A549 …

    Date Published:
    2020-04
    Record Visibility:
    Public
  • 5

    Doctoral Dissertation

    Author:
    Jinhe Ye
    Advisory Committee:
    Sergei Starchenko
    Degree Area:
    Mathematics
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-05-04
    Record Visibility:
    Public
  • 6

    Doctoral Dissertation

    Author:
    Leo Jimenez
    Advisory Committee:
    Anand Pillay
    Degree Area:
    Mathematics
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-05-20
    Record Visibility:
    Public
  • Author(s):
    Frederik J. Steyn, Siobhan Kirk, Tesfay W. Tefera, Teresa Xie, Timothy Tracey, Dean Kelk, Elyse Wimberger, Fleur Garton, Llion Robets, Sarah Chapman, Jeff Coombes, W. Matthew Leevy, Alberto Ferri, Cristiana Valle, Frederique Rene, Jean-Philippe Loeffler, Pamela McCombe, Robert Henderson, Shyuan Ngo
    Abstract:

    Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of upper and lower 36 motor neurons, yet an increasing number of studies in both mouse models and patients with 37 ALS suggest that altered metabolic homeostasis is a feature of disease. Pre-clinical and clinical 38 studies have shown that modulation of energy balance can be beneficial in ALS. However, our 39 capacity to target specific metabolic pathways or mechanisms requires detailed understanding 40 of metabolic dysr…

    Date Published:
    2020-04
    Record Visibility:
    Public
  • Author:
    Mallika S. Sarma
    Advisory Committee:
    Agustín Fuentes, Cara Ocobock, Lee T. Gettler, James J. McKenna
    Degree Area:
    Anthropology
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-05-05
    Record Visibility:
    Public
  • Author:
    Lina Cao
    Advisory Committee:
    Patrick J. Fay
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-05-14
    Record Visibility:
    Public
  • Author:
    Reginald (Brendan) Lynch
    Advisory Committee:
    Joseph P. Wawrykow
    Degree Area:
    Theology
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-04-27
    Record Visibility:
    Public
  • Author(s):
    Jeff Harden
    Abstract:

    Governments around the world adopt transparency reforms to facilitate accountability. In principle, open proceedings provide citizens with valuable information to evaluate elected officials’ decisionmaking, which incentives lawmakers to follow mass preferences when choosing policies. However, the public’s general lack of knowledge and engagement with the political process may weaken the power of open information, and perhaps instead allow citizens and groups with extreme views to exer…

    Record Visibility:
    Public
  • Author(s):
    Brenna Moore
    Abstract:

    In early twentieth-century France, a vast network of artists, writers, and religious seekers were drawn to Roman Catholicism’s elaborate panoply of symbols centered on suffering. A preoccupation with affliction dominated the movement now known as the French Catholic revival, or the renouveau catholique—considered a watershed in the history of the modern Catholic Church and the “golden age” of French Catholicism. In Sacred Dread, Brenna Moore examines the life and writings o…

    Date Created:
    2012-12-15
    Record Visibility:
    Public
    Resource Type
    Book