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  • Author(s):
    Adam S. Braegelman, Rachel C. Ollier, Bo Su, Christopher J. Addonizio, Lei Zou, Sara L. Cole, Matthew J. Webber
    Abstract:

    Hydrogels prepared from supramolecular cross-linking motifs are appealing for use as biomaterials and drug delivery technologies. The inclusion of macromolecules (e.g., protein therapeutics) in these materials is relevant to many of their intendeduses. However, the impact of dynamic network cross-linking on macromolecule diffusion must be better understood. Here, hydrogel networks with identical topology but disparate cross-link dynamics are explored. These materials are prepared from cross-l…

    Date Published:
    2022-05
    Record Visibility:
    Public
  • Author:
    Emmanuel Cannady
    Advisory Committee:
    Rory M. McVeigh, Kraig Beyerlein, Erika Summers-Effler, Calvin Zimmermann, Jennifer Jones
    Degree Area:
    Sociology
    Degree:
    Doctor of Philosophy
    Defense Date:
    2022-06-16
    Record Visibility:
    Public
  • Author:
    Vítor Albiero
    Advisory Committee:
    Kevin W. Bowyer
    Degree Area:
    Computer Science and Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2022-06-02
    Record Visibility:
    Public
  • Author:
    Emma Rosenberg
    Advisory Committee:
    Andrew C. Gould
    Degree Area:
    Political Science
    Degree:
    Doctor of Philosophy
    Defense Date:
    2022-05-25
    Record Visibility:
    Public
  • Author:
    Raymond Lawrence Drause
    Advisory Committee:
    Semion Lyandres
    Degree Area:
    History
    Degree:
    Doctor of Philosophy
    Defense Date:
    2022-05-03
    Record Visibility:
    Public
  • Author:
    Paul David Wheatley
    Advisory Committee:
    David N. Lincicum, Robin M. Jensen
    Degree Area:
    Theology
    Degree:
    Doctor of Philosophy
    Defense Date:
    2022-06-03
    Record Visibility:
    Public
  • Author:
    Joseph N. Laski
    Advisory Committee:
    David A. Smith, David Watson, E. Mark Cummings
    Degree Area:
    Psychology, Research and Experimental
    Degree:
    Master of Arts
    Defense Date:
    2022-04-22
    Record Visibility:
    Public
  • Author(s):
    Mercedes A. Bravo, Marie Lynn Miranda
    Abstract:

    Background: Previous studies observed associations between prenatal exposure to fine particulate matter (≤ 2.5 μm; PM2.5) and small-for-gestational-age (SGA) birth and lower birthweight percentile for gestational age. Few, if any, studies examine prenatal air pollution exposure and these pregnancy outcomes in neonates born to the same women. Here, we assess whether prenatal exposure to ambient fine particulate matter (PM2.5) is associated with small-for-gestational-age (SGA) birth or birthwe…

    Date Published:
    2022-01
    Record Visibility:
    Public
  • Author(s):
    Steven J. Krieg, Carolina Avendano, Evan Grantham-Brown, Aaron Lilienfeld Asbun, Jennifer J. Schnur, Marie Lynn Miranda, Nitesh V. Chawla
    Abstract:

    COVID-19 remains a global threat in the face of emerging SARS-CoV-2 variants and gaps in vaccine administration and availability, and organizations must be prepared to detect and mitigate its risk to their people and activities. In this report we share key lessons learned from an adaptive COVID-19 testing program implemented at a mid-sized university in the Midwest. The program utilized two simple, diverse, and easily interpretable machine learning models to quickly and accurately predict whi…

    Date Published:
    2022-02
    Record Visibility:
    Public
  • Author(s):
    Samantha M. Hall, Sharon Zhang, Kate Hoffman, Marie Lynn Miranda, Heather M. Stapleton
    Abstract:

    Per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants commonly detected in human serum. Previous studies have observed associations between maternal serum PFAS and adverse pregnancy and birth outcomes such as lower birth weight or pre-eclampsia; however, few studies have explored these associations with birth outcomes and placental tissue PFAS concentration. The placenta is a vital contributor to a healthy pregnancy and may be involved in the mechanism of PFAS r…

    Date Published:
    2022-05
    Record Visibility:
    Public
  • Author(s):
    Mercedes A. Bravo, Joshua L. Warren, Man Chong Leong, Nicole C. Deziel, Rachel T. Kimbro, Michelle L. Bell, Marie Lynn Miranda
    Abstract:

    In the United States, concentrations of criteria air pollutants have declined in recent decades. Questions remain regarding whether improvements in air quality are equitably distributed across subpopulations. We assessed spatial variability and temporal trends in concentrations of particulate matter with an aerodynamic diameter ≤2.5 μm (PM2.5) and ozone (O3) across North Carolina from 2002–2016, and associations with community characteristics. Estimated daily PM2.5 and O3 concentrations at 20…

    Date Published:
    2022-04
    Record Visibility:
    Public
  • Author(s):
    Viviana Geron, Marie Lynn Miranda
    Abstract:

    In-person instruction is more important than ever as our nation wrestles not only with a pandemic but also with myriad crises, write Viviana Geron, a student, and Marie Lynn Miranda, a provost.

    Date Published:
    2020-09
    Record Visibility:
    Public