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  • Author(s):
    Peggy Griesinger, Mikala Narlock, Jeremy Friesen, Hanna Bertoldi
    Abstract:

    The presenters will outline efforts to create a unified discovery platform for digital collections from libraries, archives, and museums. They will guide attendees through the process of designing harmonized metadata profiles for these related but very different domains, including solutions for conciliating controlled vocabularies. They will discuss the software stack’s approach to moving the harmonized data from varied back-end systems to a singular point from which they build out multiple s…

    Date Created:
    2020-03-12
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Cheri Smith
    Abstract:

    In recent years, the Hesburgh Libraries at the University of Notre Dame have developed and sustained a partnership with our campus student wellness center (The McDonald Center for Student Well-Being - aka “McWell”) that includes several programs designed to promote overall physical, mental and emotional health for our users and our library staff. Our partnership began in 2016 with the introduction of McWell’s “Let’s Talk” service (https://ucc.nd.edu/lets-talk/), which is a program d…

    Date Created:
    2019-12-18
    Record Visibility:
    Public
    Resource Type
    Presentation
  • 3

    Presentation

    Author(s):
    Mikala Narlock
    Abstract:

    Since the publication of the “FAIR Guiding Principles for scientific data management and stewardship” (Wilkinson et al., 2016), a wide-variety of sciences, mathematics, and other data-intensive fields have utilized the principles to promote reusability of data and ensure the long-term preservation of valuable outputs. In particular, domain experts and leading researchers have organized hackathons and sprints to define FAIR for their specific domains. Similarly, these domain experts have creat…

    Date Created:
    2019-11-10
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Peggy Griesinger, Mikala Narlock
    Abstract:

    While updating long-standing practices and principles to ensure robust content and metadata for both access and preservation, two case managers from the Libraries’ recently created Digital Content Oversight Team will describe their experience understanding and grappling with issues at the institutional culture level that impact the success of digital projects. (presented at NDSA DigiPres 2019)

    Date Created:
    2019-10-21
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Mikala Narlock, Peggy Griesinger
    Abstract:

    Presenters will describe the process of establishing formal project oversight for similar yet unique digital collections and projects. Attendees will be offered an inside look at the low-tech Case Manager approach, including helpful documentation, the variety of roles this process necessitates, and strategies for sustaining the practice.

    Date Created:
    2019-10-17
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang, Yinhao Zhu, Evan Nichols, Qingfei Wang, Siyuang Zhang, Cody Smith, Scott Howard
    Abstract:

    Fluorescence microscopy has enabled a dramatic development in modern biology. Due to its inherently weak signal, fluorescence microscopy is not only much noisier than photography, but also presented with Poisson-Gaussian noise where Poisson noise, or shot noise, is the dominating noise source. To get clean fluorescence microscopy images, it is highly desirable to have effective denoising algorithms and datasets that are specifically designed to denoise fluorescence microscopy images. While su…

    Date Created:
    2019-10-15
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Pat Lawton, Mikala Narlock, Patrick Rader
    Abstract:

    The process of moving digitized and born-digital materials from selection to recovery, discovery, and preservation, was ambiguous at Notre Dame, as a “favor system” had become the norm. To address the issue, the Digital Collections Workflow (DCW) team, comprised of individuals from units across the library, developed workflows based on representative and adaptable use cases. This collaborative process, fueled by shared experience, resulted in a low- tech “case manager” approach that ensures p…

    Date Created:
    2019-04-29
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy combined with fluorescence lifetime imaging microscopy (MPM-FLIM) is a technique that allows for imaging the lifetime of fluorescence created by two-photon excitation. It not only possesses the advantages of MPM such as large imaging depth, but also the strengths of FLIM including the ability to discriminate different fluorophores with similar emission spectra. In FLIM, the frequency-domain (FD) method, which relies on periodic intensity-modulated excitation light and i…

    Date Created:
    2015-10-22
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    In cancer and all biomedical researches, we always need a microscope with better imaging precision, speed, functionality, and depth, so that the diagnostics and treatments of cancer and other diseases can be accurate, fast, and noninvasive. However, conventional fluorescence microscopes cannot satisfy these needs due to physical limits on resolution, speed, information, and depth. In this work, we aim to overcome these limits using novel super-resolution microscopy and high-speed quantitative…

    Date Created:
    2018-04-09
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy (MPM) is a widely used in vivo imaging technique in biological and medical applications. In the case of two-photon excitation fluorescence, two lower-energy photons excite a fluorophore which in turn emits a single higher-energy photon, whose rate depends quadratically on the excitation intensity, thus enabling higher resolution with narrower point spread function (PSF) than conventional one-photon fluorescence microscopy. Fluorescence lifetime imaging microscopy (FLIM)…

    Date Created:
    2016-04-04
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    To fundamentally understand biological and medical phenomena such as aging and diseases, we need the information of the microenvironment surrounding living cells. We propose the multiphoton fluorescence lifetime imaging microscopy (MPM-FLIM) platform with super-sensitivity and super-resolution capabilities to quantitatively obtain this information at the intracellular level. First, we present a simple MPM oxygen imaging probe compatible with aqueous biological media based on water-soluble rut…

    Date Created:
    2017-03-30
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit, but its universal application is not feasible due to its difficult implementation and high cost. In this research, we propose and demonstrate a new kind of super-resolution fluorescence microscopy that can be easily implemented and requires neither additional hardware nor complex post-processing. The microscopy is based on the principle o…

    Date Created:
    2017-10-19
    Record Visibility:
    Public
    Resource Type
    Presentation