Bone and tissue scaffolding for delivery of therapeutic agents

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Description

The present invention provides a bone in-growth surface for implants which has a structure for delivering therapeutic agents to surrounding bone and tissue. The bone in-growth surface may comprise scaffolding and a controlled-permeability layer which contains the therapeutic agents in a variety of reservoirs. The porosity of the scaffolding may be controllable from zero porosity to essentially a fully porous material.

Attributes
Attribute NameValues
Title

  • Bone and tissue scaffolding for delivery of therapeutic agents

Patent Number

  • US 7674477 B2

USPTO Link
Inventor

  • Steven R. Schmid

  • Glen L. Niebur

  • Dale R. Sumner

Inventor From Local Institution

  • Steven R. Schmid

  • Niebur Glen L.

Other Application

  • 11/325,530

Claims

  • 40

Classification (US Patent)

  • 424/422; 424/423; 424/424; 424/425; 424/427; 604/890.1; 604/891.1;

Cooperative Patent Classification codes

  • A61F 2/28 (20130101); A61L 27/56 (20130101); A61F 2/30965 (20130101); A61F 2002/30006 (20130101); A61F 2002/30011 (20130101); A61F 2002/30062 (20130101); A61F 2002/30064 (20130101); A61F 2002/30087 (20130101); A61F 2002/30092 (20130101); A61F 2002/30677 (20130101); A61F 2002/3092 (20130101); A61F 2002/30925 (20130101); A61F 2002/30948 (20130101); A61F 2002/30957 (20130101); A61F 2002/30967 (20130101); A61F 2002/3097 (20130101); A61F 2002/30971 (20130101); A61F 2002/30978 (20130101); A61F 2210/0004 (20130101); A61F 2210/0014 (20130101); A61F 2250/0015 (20130101); A61F 2250/0023 (20130101); A61F 2310/00017 (20130101); A61F 2310/00023 (20130101); A61F 2310/00029 (20130101); A61F 2310/00041 (20130101); A61F 2310/00059 (20130101); A61F 2310/00131 (20130101); A61F 2310/00203 (20130101); A61F 2310/00239 (20130101); A61F 2310/00293 (20130101); A61F 2310/00395 (20130101); A61F 2310/0058 (20130101); A61F 2310/00592 (20130101); A61F 2310/00604 (20130101); A61F 2310/00796 (20130101); A61F 2310/0097 (20130101)

International Patent Classification codes

  • A61K 9/22 (20060101); A61F 2/02 (20060101)

Language

  • eng

Date Issued

  • 2010-03-09

Publisher

  • United States Patent and Trademark Office

Assignee

  • University of Notre Dame Du Lac

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