Phthalanilate compounds and methods of use

Patent

Description

The invention provides antimicrobial compounds and compositions, and methods of using them. The compounds and compositions include, for example, a compound of any one of Formulas I-X. The invention further provides methods of preparing the compounds, and useful intermediates for their preparation. The compounds can possess highly specific and selective activity, such as antibacterial activity and/or enzymatic inhibitory activity. Accordingly, the compounds and compositions can be used to treat bacterial infections, or to inhibit or kill bacteria, either in vitro or in vivo.

Attributes

Attribute NameValues
Title
  • Phthalanilate compounds and methods of use

Patent Number
  • US 8859620 B2

USPTO Link
Inventor
  • Shahriar Mobashery

  • Dusan Hesek

  • Mayland Chang

Inventor From Local Institution
  • Shahriar Mobashery

  • Dusan Hesek

  • Mayland Change

Other Application
  • 13/393,436

Prior Publication Date
  • 2012-09-13

Prior Publication Number
  • US 20120232150 A1

Claims
  • 21

Classification (US Patent)
  • 514/562; 514/563

Cooperative Patent Classification codes
  • C07C 233/15 (20130101); C07C 235/74 (20130101); C07C 233/59 (20130101); C07C 233/60 (20130101); C07C 233/66 (20130101); C07C 233/69 (20130101); C07C 233/73 (20130101); C07C 233/75 (20130101); C07C 233/81 (20130101); C07C 235/16 (20130101); C07C 271/58 (20130101); C07C 327/48 (20130101); C07C 333/08 (20130101); C07D 209/46 (20130101); C07D 213/75 (20130101); C07D 295/108 (20130101); C07D 295/135 (20130101); C07D 307/52 (20130101); C07D 339/08 (20130101); C07D 495/04 (20130101); C07D 501/34 (20130101); C07D 319/16 (20130101); C07D 295/192 (20130101); C07D 295/155 (20130101); C07D 215/40 (20130101); C07C 235/84 (20130101); C07D 513/04 (20130101); C07C 233/26 (20130101); C07C 2601/02 (20170501); C07C 2601/08 (20170501); C07C 2601/14 (20170501)

International Patent Classification codes
  • A61K 31/195 (20060101); A01N 37/12 (20060101); A01N 37/44 (20060101)

Language
  • English

Date Issued
  • 2014-10-14

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

Record Visibility and Access Public
Content License
  • All rights reserved

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