Method for detecting phosphatidylserine on the surface of cells

Patent

Description

The present invention relates generally to a method and compound for sensing the presence of anionic phospholipids, especially phosphatidylserine, on the surface of vesicles and cells. Upon introducing a compound having the structure below to a sample of cells or vesicles, the compound binds to anionic phopholipids on the surface of cells or vesicles and the presence of the compound is detected reflecting the presence of anionic phospholipids in the sample ##STR00001##

Attributes

Attribute NameValues
Title
  • Method for detecting phosphatidylserine on the surface of cells

Patent Number
  • US 7179616 B2

USPTO Link
Inventor
  • Bradley D. Smith

Inventor From Local Institution
  • Bradley D. Smith

Other Application
  • 10/656,237

Claims
  • 5

Classification (US Patent)
  • 435/40.5; 436/172; 436/501; 436/800; 436/86; 436/87;

Cooperative Patent Classification codes
  • G01N 1/30 (20130101); Y10S 436/80 (20130101); G01N 2405/04 (20130101); G01N 15/1475 (20130101)

International Patent Classification codes
  • G01N 1/30 (20060101); G01N 21/76 (20060101); G01N 33/533 (20060101)

Language
  • eng

Date Issued
  • 2007-02-20

Publisher
  • United States Patent and Trademark Office

Assignee
  • University of Notre Dame Du Lac

Record Visibility Public
Content License
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