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Method for detecting phosphatidylserine on the surface of cells

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posted on 2016-06-07, 00:00 authored by Bradley D SmithBradley D Smith
The present invention relates generally to a method and compound for sensing the presence of anionic phospholipids, especially phosphatidylserine, on the surface of vesicles and cells. Upon introducing a compound having the structure below to a sample of cells or vesicles, the compound binds to anionic phopholipids on the surface of cells or vesicles and the presence of the compound is detected reflecting the presence of anionic phospholipids in the sample ##STR00001##

History

Patent Number

US 7179616 B2

Other Application

10/656,237

USPTO Link

Inventor

Bradley D. Smith

Inventor from Local Institution

Bradley D. Smith

Assignee

University of Notre Dame Du Lac

Date Modified

2016-06-07

Language

  • English

Claims

5

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

G01N 1/30 (20130101); Y10S 436/80 (20130101); G01N 2405/04 (20130101); G01N 15/1475 (20130101)

Contributor

Bradley D. Smith

International Patent Classification Codes

G01N 1/30 (20060101); G01N 21/76 (20060101); G01N 33/533 (20060101)

US Patent Classification Codes

435/40.5; 436/172; 436/501; 436/800; 436/86; 436/87;

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    Licence

    CC BY 4.0

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