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Derivatives of epothilone B and D and synthesis thereof

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posted on 2016-06-07, 00:00 authored by Richard E. Taylor, Yue Chen
The present invention provides the following new compounds: (R)-C14-methyl-epothilone B, (S)-C14-methyl-epothilone B, (S)-C14-methyl-epothilone D, and (R)-C14-methyl-epothilone D and methods for synthesizing these compounds.

History

Patent Number

US 6900331 B2

Other Application

10/375,100

Inventor

Richard E. Taylor Yue Chen

Inventor from Local Institution

Richard E. Taylor

Assignee

University of Notre Dame Du Lac

Date Modified

2016-06-07

Language

  • English

Claims

12

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 493/04 (20130101); C07D 417/06 (20130101)

Contributor

Richard E. Taylor|

International Patent Classification Codes

A61K 31/427 (20060101); C07D 277/00 (20060101); C07D 277/20 (20060101); C07D 417/00 (20060101); C07D 417/02 (20060101); C07D 277/20

US Patent Classification Codes

548/204; 548/2;

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