8,635,028 OCR.pdf (1.1 MB)
Rapid detection of viable bacteria system and method
An improved system and method is provided for detecting viable bacteria in a suspension sample. A sample of a suspension in which bacterial presence is suspected is collected from a source and a portion of the sample transferred to a microfluidic unit. A series of analysis signals at different frequencies are applied to the sample portion. An impedance is measured via a signal analyzer for the sample portion for each of the analysis signals to define an impedance data set. An initial bulk capacitance value is determined for a model circuit based on the impedance dataset. After a predetermined time period, a new bulk capacitance value is determined for on another portion of the sample. The difference between the new bulk capacitance and the initial bulk capacitance value is compared to a threshold value to determine if viable bacterial is present in the sample.
History
Patent Number
US 8635028 B2Other Application
12/896,188Inventor
Shramik Sengupta Hsueh-Chia ChangInventor from Local Institution
Hsueh-Chia ChangAssignee
The Curators of the University of Missouri (Columbia, MO) University of Notre Dame du LacDate Modified
2017-06-22Language
- English
Claims
18Prior Publication Number
US 20110081676 A1Publisher
U.S. Patent and Trademark OfficeCooperative Patent Classification Codes
C12Q 1/04 (20130101); G01N 33/5438 (20130101); C12Q 1/06 (20130101); B01L 3/502715 (20130101)Contributor
Hsueh-Chia ChangInternational Patent Classification Codes
G01N 33/50 (20060101)US Patent Classification Codes
702/19Usage metrics
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