9,159,537 OCR.pdf (1.59 MB)

Method for analyzing sample components

standard

posted on 2017-08-01, 00:00 authored by Guijie Zhu, James McGivney, Norman Dovichi

Described herein is a method and system for on-line coupling of capillary isoelectric focusing (cIEF) to high-resolution mass spectrometry in which a sheath flow buffer comprising polar organic solvent and organic acid is used as both an immobilization solution for (cIEF) and an ionization solution for electrospray ionization (ESI).

History

Patent Number

US 9159537 B2

Other Application

14/395,862

USPTO Link

http://patft1.uspto.gov/netacgi/nph-Parser?patentnumber=9159537

Inventor

James McGivney Guijie Zhu Norman Dovichi

Inventor from Local Institution

Guijie Zhu Norman Dovichi

Assignee

University of Notre Dame du Lac Medimmune, LLC (Gaithersburg, MD)

Date Modified

2017-08-01

Language

English

Claims

20

Prior Publication Number

US 20150162177 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

G01N 27/447 (20130101); H01J 49/0031 (20130101); H01J 49/165 (20130101); H01J 49/26 (20130101); G01N 27/4473 (20130101); G01N 27/44795 (20130101)

Contributor

Guijie Zhu|Norman Dovichi

International Patent Classification Codes

C12Q 1/68 (20060101); G01N 1/00 (20060101); G01N 30/72 (20060101); H01J 49/00 (20060101); G01N 27/447 (20060101); H01J 49/26 (20060101); H01J 49/16 (20060101)

US Patent Classification Codes

1/1

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