Method for preparing largazole analogs and uses thereof

Patent

Description

Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.

Attributes

Attribute NameValues
Title
  • Method for preparing largazole analogs and uses thereof

Patent Number
  • US 9186402 B2

USPTO Link
Inventor
  • Robert M. Williams

  • James E. Bradner

  • Albert Bowers

  • Tenaya Newkirk

  • Olaf G. Wiest

Inventor From Local Institution
  • Olaf G. Wiest

Other Application
  • 13/944,446

Prior Publication Date
  • 2014-04-03

Prior Publication Number
  • US 20140093449 A1

Claims
  • 11

Classification (US Patent)
  • 1/1

Cooperative Patent Classification codes
  • C07D 498/18 (20130101); C07D 513/18 (20130101); A61K 31/429 (20130101); A61K 39/39558 (20130101)

International Patent Classification codes
  • C07D 513/18 (20060101); C07D 513/22 (20060101); C07D 498/18 (20060101); A61K 39/395 (20060101); A61K 31/429 (20060101)

Language
  • English

Date Issued
  • 2015-11-17

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • Colorado State University Research University (Fort Collins, CO)

  • Dana-Farber Cancer Institute, Inc. (Boston, MA)

  • University of Notre Dame du Lac

Record Visibility and Access Public
Content License
  • All rights reserved

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