9,186,402 OCR.pdf (4.93 MB)

Method for preparing largazole analogs and uses thereof

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posted on 2017-08-01, 00:00 authored by Albert A. Bowers, James E. Bradner, Olaf G. Wiest, Robert M. Williams, Tenaya L. Newkirk

Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.

History

Patent Number

US 9186402 B2

Other Application

13/944,446

USPTO Link

http://patft1.uspto.gov/netacgi/nph-Parser?patentnumber=9186402

Inventor

Robert M. Williams James E. Bradner Albert A. Bowers Tenaya L. Newkirk Olaf G. Wiest

Inventor from Local Institution

Olaf G. Wiest

Assignee

Colorado State University Research University (Fort Collins, CO) Dana-Farber Cancer Institute, Inc. (Boston, MA) University of Notre Dame du Lac

Date Modified

2022-01-16

Language

English

Claims

11

Prior Publication Number

US 20140093449 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 498/18 (20130101); C07D 513/18 (20130101); A61K 31/429 (20130101); A61K 39/39558 (20130101)

Contributor

Olaf G. Wiest

International Patent Classification Codes

C07D 513/18 (20060101); C07D 513/22 (20060101); C07D 498/18 (20060101); A61K 39/395 (20060101); A61K 31/429 (20060101)

US Patent Classification Codes

1/1

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