Exosomes and diagnostic biomarkers

Patent

Description

The invention provides methods for the detection of M. tuberculosis proteins in or on exosomes derived from infected individuals. The methods can use a proteomic approach including mass spectroscopy, data mining and multiplex reaction monitoring to quickly examine a large amount of M. tuberculosis proteins to determine the best biomarkers for use in diagnostic tests to identify active TB patients.

Attributes

Attribute NameValues
Title
  • Exosomes and diagnostic biomarkers

Patent Number
  • US 9255924 B2

USPTO Link
Inventor
  • Jeffrey S. Schorey

  • Karen M. Dobos

Inventor From Local Institution
  • Jeffrey S. Schorey

Other Application
  • 14/052,378

Prior Publication Date
  • 2014-04-24

Prior Publication Number
  • US 20140113305 A1

Claims
  • 11

International Patent Classification codes
  • A61K 39/04 (20060101); G01N 33/569 (20060101); G01N 33/68 (20060101); C12N 1/20 (20060101); C07K 14/35 (20060101)

Language
  • English

Date Issued
  • 2016-02-09

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

  • Colorado State University Research Foundation (Fort Collins, CO)

Record Visibility Public
Content License
  • All rights reserved

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