9,308,252 OCR.pdf (1.38 MB)
Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
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posted on 2017-08-01, 00:00 authored by Mark A. Suckow, Paul J. Hall, William R. WolterDisclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvants are demonstrated to enhance the immunogencity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal.
History
Patent Number
US 9308252 B2Other Application
11/699,448Inventor
Mark A. Suckow William R. Wolter Paul J. HallInventor from Local Institution
Mark A. Suckow William R. WolterAssignee
Cook Biotech, Inc. (West Lafayette, IN) University of Notre Dame du LacDate Modified
2017-08-01Language
- English
Claims
16Prior Publication Number
US 20080107665 A1Publisher
U.S. Patent and Trademark OfficeCooperative Patent Classification Codes
A61K 39/08 (20130101); A61K 39/39 (20130101); A61K 2039/55511 (20130101); A61K 2039/55588 (20130101)Contributor
Mark A. Suckow|William R. WolterInternational Patent Classification Codes
A61K 39/39 (20060101); A61K 39/08 (20060101); A61K 39/00 (20060101)Usage metrics
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