Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins

Patent

Description

Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvants are demonstrated to enhance the immunogencity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal.

Attributes

Attribute NameValues
Title
  • Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins

Patent Number
  • US 9308252 B2

USPTO Link
Inventor
  • Mark A. Suckow

  • William R. Wolter

  • Paul J. Hall

Inventor From Local Institution
  • Mark A. Suckow

  • William R. Wolter

Other Application
  • 11/699,448

Prior Publication Date
  • 2008-05-08

Prior Publication Number
  • US 20080107665 A1

Claims
  • 16

Cooperative Patent Classification codes
  • A61K 39/08 (20130101); A61K 39/39 (20130101); A61K 2039/55511 (20130101); A61K 2039/55588 (20130101)

International Patent Classification codes
  • A61K 39/39 (20060101); A61K 39/08 (20060101); A61K 39/00 (20060101)

Language
  • English

Date Issued
  • 2016-04-12

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • Cook Biotech, Inc. (West Lafayette, IN)

  • University of Notre Dame du Lac

Record Visibility and Access Public
Content License
  • All rights reserved

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