Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick type C disease

Patent

Description

Embodiments herein relate to the field of lysosomal storage disorders, and, more specifically, to methods of treating lysosomal storage disorders such as Niemann-Pick type C disease, for instance with inhibitors of histone deacetylases, particularly inhibitors of class 1 histone deacetylases. In various embodiments, methods of treating Niemann-Pick type C disease with inhibitors of class 1 histone deacetylases are described.

Attributes

Attribute NameValues
Title
  • Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick type C disease

Patent Number
  • US 9333222 B2

USPTO Link
Inventor
  • Olaf G. Wiest

  • Frederick R. Maxfield

  • Paul Helquist

Inventor From Local Institution
  • Olaf G. Wiest

  • Paul Helquist

Other Application
  • 12/888,267

Prior Publication Date
  • 2011-03-24

Prior Publication Number
  • US 20110071109 A1

Claims
  • 10

Cooperative Patent Classification codes
  • A61K 31/721 (20130101); A61K 31/724 (20130101); A61K 47/48092 (20130101); A61K 31/715 (20130101); A61K 31/4045 (20130101); A61K 31/165 (20130101)

International Patent Classification codes
  • A61K 31/165 (20060101); A61K 31/4045 (20060101); A61K 31/724 (20060101); A61K 47/48 (20060101); A61K 31/721 (20060101)

Language
  • English

Date Issued
  • 2016-05-10

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

  • Cornell University (Ithaca, NY)

Record Visibility and Access Public
Content License
  • All rights reserved

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