Analysis of the Genomic Architecture of Anopheles Gambiae

Doctoral Dissertation

Abstract

Malaria still kills over one million people a year, mostly children in sub-Saharan Africa. Anopheles gambiae is the main malaria vector in sub-Saharan Africa. The publication of the An. gambiae genome in 2002 opened up a vast array of information that potentially can be used in controlling this deadly mosquito. However, this vast assortment of genomic data also opened up the challenge of being able to parse through this data to identify useful information,

To help organize this data into manageable quantities this thesis focuses on three main genomic structures in An. gambiae: 1) microsatellites, 2) syntenic relationships between the genome of An. gambiae and D. melanogaster, and 3)Tc1-mariner superfamily transposable element distribution

Attributes

Attribute NameValues
URN
  • etd-07172006-105357

Author James Robert Hogan
Advisor Dr. Frank Collins
Contributor Dr Jeanne Romero-Severson, Committee Member
Contributor Dr. Joseph OTousa, Committee Member
Contributor Dr. Frank Collins, Committee Chair
Contributor Dr. Dave Severson, Committee Member
Degree Level Doctoral Dissertation
Degree Discipline Biological Sciences
Degree Name PhD
Defense Date
  • 2006-06-27

Submission Date 2006-07-17
Country
  • United States of America

Subject
  • transposable elements

  • Anopheles gambiae

  • microsatellites

  • synteny

Publisher
  • University of Notre Dame

Language
  • English

Record Visibility and Access Public
Content License
  • All rights reserved

Departments and Units

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