9,353,092 OCR.pdf (1.77 MB)
Synthesis and use of croconaine compounds
The present disclosure provides compositions and methods for the synthesis and use of croconaine compounds. The disclosed compounds are easily prepared from croconic acid. A halothiophene is reacted with an alkanolamine, the resulting aminothiophene is modified by appending a desired functional group to the hydroxyl group, and the modified aminothiophene is reacted with croconic acid to form the final compound. Applications of such croconaine compounds include photothermal imaging, photothermal therapy, light-activated drug release, and tissue welding.
History
Patent Number
US 9353092 B2Other Application
14/311,267Inventor
Bradley D. SmithInventor from Local Institution
Bradley D. SmithAssignee
University of Notre Dame du LacDate Modified
2017-08-01Language
- English
Claims
20Prior Publication Number
US 20150005501 A1Publisher
U.S. Patent and Trademark OfficeContributor
Bradley D. SmithInternational Patent Classification Codes
C07D 409/14 (20060101); C07D 409/08 (20060101)Usage metrics
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