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Supramolecular capture of highly polar amidosquaraine dye in water with nanomolar affinity and large turn-on fluorescence†

journal contribution
posted on 2022-11-17, 00:00 authored by Bradley D SmithBradley D Smith, Janel M. Dempsey, Kejia Shi, Kirk M. Atkinson, Madushani Dharmarwardana, Sasha Padilla-Coley, Tia S. Jarvis
A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and ‘‘turn on’’ visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A2.

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Date Modified

2022-11-17

Language

  • English

Publisher

Royal Society of Chemistry

Additional Groups

  • Integrated Imaging Facility

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    Chemistry and Biochemistry

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