Process for preparing .beta.-hydroxy-.alpha. amino acids

Patent

Description

.beta.-Hydroxy-.alpha.-amino acids are obtained via serine hydroxymethyltransferase catalyzed condensation of aldehydes with glycine. The predominant product with most aldehydes is the L-erythro diastereomer. For example, succinic semialdehyde methylester is condensed with glycine in the process to provide L-erythro .alpha.-amino hydroxy adipic acid mono methyl ester.

Attributes

Attribute NameValues
Title
  • Process for preparing .beta.-hydroxy-.alpha. amino acids

Patent Number
  • US 5266468 B2

USPTO Link
Inventor
  • Marvin J. Miller

Inventor From Local Institution
  • Marvin J. Miller

Other Application
  • 07/918,878

Claims
  • 3

Classification (US Patent)
  • 435/106; 564/503;

Cooperative Patent Classification codes
  • C12N 9/1014 (20130101); C12P 13/08 (20130101); C12P 13/04 (20130101)

International Patent Classification codes
  • C12P 13/00 (20060101); C12P 13/08 (20060101); C12P 13/04 (20060101); C12N 9/10 (20060101); C12P 013/04 (); C07C 215/00 ()

Language
  • eng

Date Issued
  • 1993-11-30

Publisher
  • United States Patent and Trademark Office

Assignee
  • University of Notre Dame Du Lac

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