High sensitivity electrospray interface

Patent

Description

The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.

Attributes

Attribute NameValues
Title
  • High sensitivity electrospray interface

Patent Number
  • US 9465014 B2

USPTO Link
Inventor
  • Norman Dovichi

  • Liangliang Sun

  • Guijie Zhu

Inventor From Local Institution
  • Norman Dovichi

  • Liangliang Sun

  • Guijie Zhu

Other Application
  • 14/679,009

Prior Publication Date
  • 2015-08-20

Prior Publication Number
  • US 20150233877 A1

Claims
  • 19

Cooperative Patent Classification codes
  • G01N 30/7266 (20130101); H01J 49/0445 (20130101); G01N 27/4473 (20130101); G01N 27/44743 (20130101); H01J 49/167 (20130101); H01J 49/004 (20130101); H01J 49/0404 (20130101); G01N 27/4473 (20130101); G01N 30/7266 (20130101)

International Patent Classification codes
  • H01J 49/00 (20060101); G01N 27/447 (20060101); H01J 49/04 (20060101); H01J 49/16 (20060101); G01N 30/72 (20060101)

Language
  • English

Date Issued
  • 2016-10-11

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

Record Visibility Public
Content License
  • All rights reserved

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