Tissue scaffolds having bone growth factors

Patent

Description

The invention provides a novel composite bone graft system utilizing a porous collagen scaffold having a matrix impregnated with calcium phosphate particles and more than one bioactive agent, one of which is conjugated to the matrix. The graft system exhibits increased mechanical strength and osteogenic properties by providing sites for tissue attachment and propagation. The bioactive agents are delivered to the scaffold via different mechanisms to enable sequential and sustained release of the bioactive agents over time.

Attributes

Attribute NameValues
Title
  • Tissue scaffolds having bone growth factors

Patent Number
  • US 9550012 B2

USPTO Link
Inventor
  • Ryan K. Roeder

  • Matthew J. Meagher

  • Robert J. Kane

Inventor From Local Institution
  • Ryan K. Roeder

  • Matthew J. Meagher

  • Robert J. Kane

Other Application
  • 14/452,422

Prior Publication Date
  • 2015-05-14

Prior Publication Number
  • US 20150132354 A1

Claims
  • 18

Cooperative Patent Classification codes
  • A61L 27/46 (20130101); C08L 89/06 (20130101); A61L 27/54 (20130101); A61L 27/56 (20130101); A61L 27/46 (20130101); A61K 38/18 (20130101); A61K 38/1875 (20130101); A61K 38/1866 (20130101); A61L 2300/414 (20130101); A61L 2430/02 (20130101)

International Patent Classification codes
  • A61K 38/18 (20060101); A61L 27/12 (20060101); A61L 27/24 (20060101); A61L 27/56 (20060101); A61L 27/54 (20060101); A61L 27/40 (20060101); A61L 27/46 (20060101); A61P 19/08 (20060101)

Language
  • English

Date Issued
  • 2017-01-24

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

Record Visibility and Access Public
Content License
  • All rights reserved

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