5,5-heteroaromatic anti-infective compounds

Patent

Description

The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carbox- amide.

Attributes

Attribute NameValues
Title
  • 5,5-heteroaromatic anti-infective compounds

Patent Number
  • US 9605002 B2

USPTO Link
Inventor
  • Garrett C. Moraski

  • Marvin J. Miller

Inventor From Local Institution
  • Garrett C. Moraski

  • Marvin J. Miller

Other Application
  • 14/415,726

Prior Publication Date
  • 2015-07-30

Prior Publication Number
  • US 20150210715 A1

Claims
  • 20

Cooperative Patent Classification codes
  • C07D 513/04 (20130101); A61K 9/0014 (20130101); A61K 9/0019 (20130101); A61K 9/2059 (20130101); A61K 9/2866 (20130101); A61K 31/4188 (20130101

International Patent Classification codes
  • C07D 513/04 (20060101); A61K 31/4188 (20060101); A61K 9/00 (20060101); A61K 9/28 (20060101); A61K 9/20 (20060101)

Language
  • English

Date Issued
  • 2017-03-28

Publisher
  • U.S. Patent and Trademark Office

Assignee
  • University of Notre Dame du Lac

Record Visibility and Access Public
Content License
  • All rights reserved

Departments and Units
Member of

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