Effects of calibration methods on quantitative material decomposition in photon‐counting spectral computed tomography using a maximum a posteriori estimator

Article

Abstract

Advances in photon‐counting detectors have enabled quantitative material decomposition using multi‐energy or spectral computed tomography (CT). Supervised methods for material decomposition utilize an estimated attenuation for each material of interest at each photon energy level, which must be calibrated based upon calculated or measured values for known compositions. Measurements using a calibration phantom can advantageously account for system‐specific noise, but the effect of calibration methods on the material basis matrix and subsequent quantitative material decomposition has not been experimentally investigated. Therefore, the objective of this study was to investigate the influence of the range and number of contrast agent concentrations within a modular calibration phantom on the accuracy of quantitative material decomposition in the image domain.

Attributes

Attribute NameValues
Creator
  • Tyler E. Curtis

  • Ryan K. Roeder

Publication Date
  • 2017

Date Created
  • 2018-09-08

Language
  • English

Departments and Units
Record Visibility and Access Public
Content License
  • All rights reserved

Digital Object Identifier

doi:10.1002/mp.12457

This DOI is the best way to cite this article.