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Microfluidic devices, systems, and methods for imaging tissue samples

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posted on 2019-02-18, 00:00 authored by Cody Narciso, David Hoelzle, Jeremiah Zartman, Siyuan Zhang, Victoria Zellmer, Wendy Barrios
One aspect of the present disclosure can include a microfluidic device for imaging a tissue sample. The device can include a tissue chamber, a liquid inlet channel, and a liquid outlet channel. The tissue chamber can be defined by a plurality of walls, at least one of which is transparent. The liquid inlet channel can be fluid communication with the tissue chamber. The liquid outlet channel can be in fluid communication with the tissue chamber. The tissue chamber can be sized and dimensioned to completely immobilize the tissue sample during imaging.

History

Patent Number

US 10168259 B2

Other Application

14/737,986

Inventor

Jeremiah Zartman David Hoelzle Cody Narciso Siyuan Zhang Wendy Alvarez Barrios Victoria Zellmer

Inventor from Local Institution

Jeremiah Zartman David Hoelzle Cody Narciso Siyuan Zhang Wendy Alvarez Barrios Victoria Zellmer

Assignee

University of Notre Dame Du Lac

Date Modified

2019-02-18

Language

  • English

Claims

19

Prior Publication Number

US 20150362411 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

B01L 3/5027 (20130101); G02B 21/34 (20130101); G01N 1/312 (20130101); B01L 2300/0645 (20130101); B01L 2400/0439 (20130101); B01L 3/54 (20130101); B01L 2300/0654 (20130101); B01L 2400/0421 (20130101); B01L 2400/0487 (20130101)

Contributor

Jeremiah Zartman|David Hoelzle|Cody Narciso|Siyuan Zhang|Wendy Alvarez Barrios|Victoria Zellmer

International Patent Classification Codes

G01N 1/31 (20060101); B01L 3/00 (20060101); G02B 21/34 (20060101); G01N 1/28 (20060101)

Additional Groups

  • Chemical and Biomolecular Engineering
  • Aerospace and Mechanical Engineering
  • Biological Sciences
  • Harper Cancer Research Institute

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