US8389223.pdf (3.17 MB)
Probes for anionic cell surface detection
Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
History
Patent Number
US 8389223 B2Other Application
12/874,689Inventor
Bradley D. SmithInventor from Local Institution
Bradley D. SmithAssignee
University of Notre Dame Du LacDate Modified
2016-06-07Language
- English
Claims
2Prior Publication Number
US 20100331542 A1Publisher
United States Patent and Trademark OfficeCooperative Patent Classification Codes
C12Q 1/04 (20130101); G01N 33/92 (20130101); G01N 2510/00 (20130101)Contributor
Bradley D. SmithInternational Patent Classification Codes
G01N 33/53 (20060101); C07F 15/04 (20060101)US Patent Classification Codes
435/7.1; 435/7.21; 435/7.23; 546/12;Usage metrics
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