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Methods and apparatus for mass spectrometry utilizing an AC electrospray device
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posted on 2017-06-22, 00:00 authored by Catherine Cassou, David Go, Hsueh-Chia ChangHsueh-Chia Chang, Nishant ChetwaniAn alternating current electrospray mass spectrometry device includes an electrospray device having at least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mobility ions in the liquid cone. The AC electric field causes the emitter to discharge the liquid cone as a liquid aerosol drop, and a mass spectrometry device analyzes the ionized analyte sample to determine the composition of the contained analyte sample.
History
Patent Number
US 8716675 B2Other Application
13/095,288Inventor
Nishant Chetwani Catherine Cassou David Go Hsueh-Chia ChangInventor from Local Institution
David Go Hsueh-Chia ChangAssignee
University of Notre Dame du LacDate Modified
2017-06-22Language
- English
Claims
16Prior Publication Number
US 20120199732 A1Publisher
U.S. Patent and Trademark OfficeCooperative Patent Classification Codes
H01J 49/165 (20130101); B05B 5/0255 (20130101)Contributor
David Go|Hsueh-Chia ChangInternational Patent Classification Codes
H01J 49/10 (20060101)US Patent Classification Codes
250/424; 250/288; 250/423RAdditional Groups
- Aerospace and Mechanical Engineering
- Chemical and Biomolecular Engineering
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