Methods and apparatus for mass spectrometry utilizing an AC electrospray device



An alternating current electrospray mass spectrometry device includes an electrospray device having at least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mobility ions in the liquid cone. The AC electric field causes the emitter to discharge the liquid cone as a liquid aerosol drop, and a mass spectrometry device analyzes the ionized analyte sample to determine the composition of the contained analyte sample.


Attribute NameValues
  • Methods and apparatus for mass spectrometry utilizing an AC electrospray device

Patent Number
  • US 8716675 B2

  • Nishant Chetwani

  • Catherine Cassou

  • David Go

  • Hsueh-Chia Chang

Inventor From Local Institution
  • David Go

  • Hsueh-Chia Chang

Other Application
  • 13/095,288

Prior Publication Date
  • 2012-08-09

Prior Publication Number
  • US 20120199732 A1

  • 16

Classification (US Patent)
  • 250/424; 250/288; 250/423R

Cooperative Patent Classification codes
  • H01J 49/165 (20130101); B05B 5/0255 (20130101)

International Patent Classification codes
  • H01J 49/10 (20060101)

  • English

Date Issued
  • 2014-05-06

  • U.S. Patent and Trademark Office

  • University of Notre Dame du Lac

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