Method and apparatus for AC electrospray

Patent

Description

The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, osteogenic or dermatological growth factors, bacteria, viruses, immobilized enzyme receptors and fluorescent particles for controlled release drug delivery, tissue or bone engineering, clinical or environmental field testing and as biosensors for clinical or drug monitoring. In addition, the present invention may be used to synthesize biodegradable fibers as bioscaffolds for tissue engineering, surgical sutures or medical gauze that enhance blood coagulation, and further may be encapsulated by other agents.

Attributes

Attribute NameValues
Title
  • Method and apparatus for AC electrospray

Patent Number
  • US 8267914 B1

USPTO Link
Inventor
  • Hsueh-Chia Chang

  • Shau-Chun Paul Wang

  • Dmitri Lastochkin

  • Leslie Yeo

  • Zachary Gagnon

Inventor From Local Institution
  • Hsueh-Chia Chang

  • Shau-Chun Paul Wang

  • Dmitri Lastochkin

  • Leslie Yeo

  • Zachary Gagnon

Other Application
  • 10/965,834

Claims
  • 41

Classification (US Patent)
  • 604/500; 128/200.14; 604/173; 604/20

Cooperative Patent Classification codes
  • A61M 11/00 (20130101); A61M 15/02 (20130101); A61K 9/0073 (20130101); A61M 2037/0061 (20130101)

International Patent Classification codes
  • A61M 31/00 (20060101)

Language
  • eng

Date Issued
  • 2012-09-18

Publisher
  • United States Patent and Trademark Office

Assignee
  • University of Notre Dame Du Lac

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